Introduce first-of-its-kind predictive hypotension monitoring technology and share clinical experience on use of HPI(hypotension prediction index) parameter

Understanding what hypotension prediction index(HPI) is and how to utilize it

Understanding clinical application on hypotension prediction index(HPI) parameter

Learning experience through case study

In this lecture, the pharmacokinetics and pharmacodynamics of dexmedetomidine will be discussed shortly. Next, we will discuss the available PKPD models and the new model developed by Hannivoort-Colin from our research group. Based on this model, the time course of drug effects such as cerebral drug effects and hemodynamic effects will be discussed. We will also discuss the interaction between dexmedetomidine and remifentanil.

Learning about the pharmacokinetic and dynamic properties of dexmedetomidine

Learning about optimizing dexmedetomidine drug administration using TCI

Understand that patients who have a hip fracture are at substantial risk of major complications (ie, cardiovascular, infectious, bleeding, and neurocognitive) and mortality.

Understand that hip fractures result in pain, bleeding, and immobility, and activate inflammatory, hypercoagulable, catabolic, and stress states that can precipitate medical complications.

Discuss the findings of the HIP attack mRCT: accelerated surgery compared with standard care resulted in a lower risk of delirium, urinary tract infection, moderate-to-severe pain, faster mobilization, and a shorter time to hospital discharge.